Bryan Johnson has consistently been fixated on making himself younger. This 46-year-old millionaire, who amassed wealth through founding several tech ventures, has invested substantial time and money striving to make his physique mirror that of a young adult. His wellness routine incorporates consuming 54 distinct supplements each morning. These tablets ostensibly assist him in prolonging his life and, as he expressed, “set the world record in reversing age.” Nonetheless, in recent times, Johnson ceased consuming at least one of those supplements out of concern that, instead of rejuvenating him, it was actually “speeding up” his aging.

In November, Johnson shared on Twitter that he had stopped using a supplement identified as rapamycin. “Despite the vast promise shown in pre-clinical studies, my team and I concluded that the advantages of lifetime usage of Rapamycin are outweighed by the considerable side-effects (sporadic skin/soft tissue infections, lipid irregularities, glucose surges, and heightened resting heart rate),” he explained. “Given no other underlying causes detected, we suspected Rapamycin, and since modification of doses yielded no change, we opted to cease its use entirely.”

He further stated: “Additionally, on October 27th, a fresh pre-print suggested that Rapamycin was among a limited number of touted longevity interventions to elevate/accelerate aging in humans based on 16 epigenetic aging assessments.”

To put it differently, after utilizing this investigative drug for five years, a new research emerged indicating it might be achieving the complete contrary of Johnson’s intentions and could also be leading to him developing skin infections.

Johnson, whose preoccupation with extending life prompted him to initiate a novel health and wellness enterprise titled Blueprint, is additionally featured in a recent Netflix documentary. The film cites Johnson claiming he has “the most assertive rapamycin” usage within “anyone in the industry,” as reported by the New York Post. “I use this because there are possibly some longevity advantages,” he mentions, highlighting it’s “the type of topic within the longevity circle that folks are enthusiastic about,” while “outside this circle, it still appears somewhat irrational.”

Most of Johnson’s longevity propositions aren’t particularly revolutionary. His fundamental guidelines for prolonged life, as recommended by his Blueprint platform, encompass actions such as abstaining from alcohol and tobacco, maintaining a nutritious eating plan, and engaging in physical activity for a few hours every week. Blueprint offers subscriptions to bags containing various protein powders, which the firm labels “longevity mixes.” A recent critique of this subscription service described it as “merely another supplement commodity, albeit featuring a very intriguing personality and narrative behind its inception.” The evaluation also highlighted that while the powder routine contained “several beneficial elements,” it was ultimately quite costly and might not be suitable for diverse populations.

Although Blueprint may seem somewhat ordinary, Johnson’s personal experiments are certainly not. In previous attempts, he has used the blood from his own teenage son to assess whether transfusions from a younger individual delivered any specific health benefits to a person his age (he has since determined that they do not), and more recently, applied “shock treatments” to his genitalia in a seemingly bizarre attempt to reverse the age of his penis and thereby elicit the erections akin to that of an 18-year-old. The outcome of Johnson’s unusual self-testing remains uncertain. Currently, we mainly observe the physical results, which thus far are not promising. Johnson, who once resembled an average individual, now self-describes as resembling a vampire.